Carl Zimmer is talking crazy talk:
The scientists propose that several centuries ago, a histiocyte cell in a dog or a wolf turned cancerous. A mutation may have caused the cell to become abnormal--perhaps that LINE-1 element that marks Sticker's sarcoma cells today. But natural selection would have favored other mutations as well that allowed its descendants to become more effective at growing into a tumor. During mating, some of the cancer cells managed to spread to the dog's partner, where they could continue to proliferate....
So here's the big question which the authors don't tackle head on: what is this thing? Is it a medieval Chinese dog that has found immortality? If so, then it resembles HeLa cells, a line of cancer cells isolated from a woman named Henrietta Lacks who died in 1951. After her death, scientists have propagated her cells, and in that time they have have adapted to their new ecological niche of Petri dishes, acquiring mutations that make it grow aggressively in the lab. One biologist even suggested that the cells should be consider a new species.
Seriously, read the whole thing.
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August 16, 2006


